Nature Communications (Jan 2018)

Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type I interferon immune responses

  • Hyun jin Choi,
  • Areum Park,
  • Sujin Kang,
  • Eunhye Lee,
  • Taeyun A. Lee,
  • Eun A. Ra,
  • Jiseon Lee,
  • Sungwook Lee,
  • Boyoun Park

DOI
https://doi.org/10.1038/s41467-017-02624-8
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 16

Abstract

Read online

MAVS and STING signaling are central to interferon-inducing antiviral immunity. Here, the authors show how the human cytomegalovirus protein US9 can evade this immunity by antagonizing these pathways.