Orbital plasmablastic lymphoma: a clinico-pathological correlation of a rare disease and review of literature

Abstract

Kaustubh Mulay,1 Mohammad Javed Ali,2 Vijay Anand Reddy,2 Santosh G Honavar21Ocular Pathology Service, LV Prasad Eye Institute, Hyderabad, Andhra Pradesh, India; 2Oncology Service, LV Prasad Eye Institute, Hyderabad, Andhra Padresh, IndiaAbstract: Ocular involvement by plasmablastic lymphoma is extremely rare with very few reports in the literature. Its morphological and immunological resemblance to plasma cell myeloma makes it a diagnostic challenge, while its clinical course, which is characterized by recurrence and death, makes therapy a challenge for clinicians. We present three cases of plasmablastic lymphoma, each of which has distinct clinicoradiological features, and we also review the literature on orbital plasmablastic lymphomas.Keywords: plasmablastic lymphoma, ocular, myeloma, orbit