Joint effects of PPARG-C161T (rs3856806) polymorphism and cardiovascular risk factors on restenosis risk after coronary stent implantation

Javadova Zahra; Yanar Fatih; Aslan Ezgi Irmak; Ozkara Gulcin; Malikova Fidan; Kilicarslan Onur; Ser Ozgur Selim; Yildiz Ahmet; Kucukhuseyin Ozlem; Ozturk Oguz; Yilmaz Aydogan Hulya

doi:10.1515/tjb-2024-0021

Türk Biyokimya Dergisi (Jun 2024)

Joint effects of PPARG-C161T (rs3856806) polymorphism and cardiovascular risk factors on restenosis risk after coronary stent implantation

Javadova Zahra,
Yanar Fatih,
Aslan Ezgi Irmak,
Ozkara Gulcin,
Malikova Fidan,
Kilicarslan Onur,
Ser Ozgur Selim,
Yildiz Ahmet,
Kucukhuseyin Ozlem,
Ozturk Oguz,
Yilmaz Aydogan Hulya

Affiliations

Javadova Zahra: Department of Molecular Medicine, 37516Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye
Yanar Fatih: Department of Molecular Medicine, 37516Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye
Aslan Ezgi Irmak: Department of Molecular Medicine, 37516Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye
Ozkara Gulcin: Department of Molecular Medicine, 37516Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye
Malikova Fidan: Department of Molecular Medicine, 37516Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye
Kilicarslan Onur: Department of Cardiology, 532719Institute of Cardiology, Istanbul University-Cerrahpasa, Istanbul, Türkiye
Ser Ozgur Selim: Department of Cardiology, 532719Institute of Cardiology, Istanbul University-Cerrahpasa, Istanbul, Türkiye
Yildiz Ahmet: Department of Cardiology, 532719Institute of Cardiology, Istanbul University-Cerrahpasa, Istanbul, Türkiye
Kucukhuseyin Ozlem: Department of Molecular Medicine, 37516Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye
Ozturk Oguz: Department of Molecular Medicine, 37516Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye
Yilmaz Aydogan Hulya: Department of Molecular Medicine, 37516Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye

DOI: https://doi.org/10.1515/tjb-2024-0021
Journal volume & issue: Vol. 49, no. 4
pp. 568 – 577

Abstract

Read online

The peroxisome proliferator-activated receptor gamma (PPARG) C161T polymorphism (rs3856806) may be a risk factor for in-stent restenosis (ISR) due to its known associations with type 2 diabetes (T2DM), obesity, and coronary artery disease (CAD). This study aims to investigate the relationship between PPARG-C161T polymorphism and the risk of ISR, considering clinical features.

Published in Türk Biyokimya Dergisi

ISSN: 1303-829X (Online)
Publisher: De Gruyter
Country of publisher: Germany
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.degruyter.com/journal/key/tjb/html

About the journal

Abstract

Keywords