Preliminary pharmacological activity of the methanolic extract of Premna integrifolia barks in rats

Hajera Khatun; Rajib Majumder; Efte Kharul Alam; Al Mamun; Safkath Ibne Jami; Badrul Alam

Avicenna Journal of Phytomedicine (May 2014)

Preliminary pharmacological activity of the methanolic extract of Premna integrifolia barks in rats

Hajera Khatun,
Rajib Majumder,
Efte Kharul Alam,
Al Mamun,
Safkath Ibne Jami,
Badrul Alam

Affiliations

Hajera Khatun: Department of Pharmacy, Southeast University, Dhaka, Bangladesh
Rajib Majumder: Department of Pharmacy, Atish Dipankar University of Science and Technology, Dhaka, Bangladesh
Efte Kharul Alam: Department of Pharmacy, Atish Dipankar University of Science and Technology, Dhaka, Bangladesh
Al Mamun: Department of Pharmacy, Rajshahi University, Rajshahi, Bangladesh
Safkath Ibne Jami: Department of Pharmacy, University of Asia Pacific, Dhaka, Bangladesh
Badrul Alam: Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh

Journal volume & issue: Vol. 4, no. 3
pp. 215 – 224

Abstract

Read online

Objective: Premna integrifolia Linn (Family: Verbenaceae) synonym of Premna serratifolia has tremendous medicinal value. Preliminary pharmacological studies were performed on the methanolic extract of Premna integrifolia (MEPI) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. Materials and methods: Neuropharmacology study was done by open field and hole cross test whereas acetic acid writhing test and formalin induced pain was done for analgesic activity of MEPI. Carrageenan induced inflammatory model was considered for anti-inflammatory activity evaluation. Results: A statistically significant (p

Published in Avicenna Journal of Phytomedicine

ISSN: 2228-7930 (Print); 2228-7949 (Online)
Publisher: Mashhad University of Medical Sciences
Country of publisher: Iran, Islamic Republic of
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: http://ajp.mums.ac.ir/

About the journal

Abstract

Keywords