Development of high-throughput ATR-FTIR technology for rapid triage of brain cancer

Holly J. Butler; Paul M. Brennan; James M. Cameron; Duncan Finlayson; Mark G. Hegarty; Michael D. Jenkinson; David S. Palmer; Benjamin R. Smith; Matthew J. Baker

doi:10.1038/s41467-019-12527-5

Nature Communications (Oct 2019)

Development of high-throughput ATR-FTIR technology for rapid triage of brain cancer

Holly J. Butler,
Paul M. Brennan,
James M. Cameron,
Duncan Finlayson,
Mark G. Hegarty,
Michael D. Jenkinson,
David S. Palmer,
Benjamin R. Smith,
Matthew J. Baker

Affiliations

Holly J. Butler: WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre
Paul M. Brennan: Translational Neurosurgery, Department of Clinical Neurosciences, Western General Hospital
James M. Cameron: WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre
Duncan Finlayson: WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre
Mark G. Hegarty: ClinSpec Diagnostics Limited, University of Strathclyde, Technology and Innovation Centre
Michael D. Jenkinson: Institute of Translational Medicine, University of Liverpool & The Walton Centre NHS Foundation Trust, Lower Lane, Fazakerley
David S. Palmer: WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre
Benjamin R. Smith: WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre
Matthew J. Baker: WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre

DOI: https://doi.org/10.1038/s41467-019-12527-5
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 9

Abstract

Read online

Diagnosing brain cancer is frequently difficult and requires specialist equipment. Here, the authors develop their previous attenuated total reflectance-Fourier transform infrared spectroscopy method and incoporate the use of disposable silicon wafers for diagnosing brain cancer using serum samples.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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