Interactive effect of eight weeks combined training and curcumin consumption on serum levels of interleukin-12 and some anthropometric indicators in obese sedentary woman

Abstract

Background: Activity has turned away from the human body by machine life and has replaced with obesity. This study aimed to investigate the interactive effect of eight weeks combined training and curcumin consumption on serum levels of interleukin-12 and some anthropometric indicators in obese sedentary woman. Materials and Methods: Semi-experimental study, Forty-eight obese women with an age range of 20-30 years were purposefully selected and divided into four groups of 12 people: control, curcumin, exercise and exercise+curcumin and for eight weeks to do combination exercises (aerobic exercise with an intensity of 60 to 80% of the MHR and resistance training with an intensity of 55 to 75% of a maximum repetition) and daily intake of curcumin of 80 mg. Fasting blood samples were taken before and after the last training session and interleukin-12 levels were measured by ELISA using kits. Data were analyzed using dependent t-test and one-way analysis of variance and significance level less than 0.05 in SPSS-22. Result: There was a significant difference in levels of interleukin-12 and body mass index between the groups of exercise, exercise+curcumin and curcumin consumption compared to the pretest (p<0.05 intragroup). The difference between pre- and post-test group differences on levels of interleukin-12 and body mass index was significantly different between the research groups (p<0.05 between groups). Conclusion: Eight weeks of combined training and curcumin consumption had a significant change in levels of IL-12. Physical activity causes weight loss and thus a decrease in body mass index, but the consumption of curcumin alone does not change the anthropometric indicators of individuals.

Keywords

• circuit-based exercise
• curcumin
• interleukin-12
• health status indicators
• obese sedentary women