Nature Communications (May 2022)

Transcriptional adaptation of olfactory sensory neurons to GPCR identity and activity

  • Luis Flores Horgue,
  • Alexis Assens,
  • Leon Fodoulian,
  • Leonardo Marconi,
  • Joël Tuberosa,
  • Alexander Haider,
  • Madlaina Boillat,
  • Alan Carleton,
  • Ivan Rodriguez

DOI
https://doi.org/10.1038/s41467-022-30511-4
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 16

Abstract

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Olfaction in mammals relies on a toolbox composed of a varied set of sensory neurons. Here, the authors report in mice that this olfactory neuronal diversity relies both on the chemoreceptor that each neuron expresses and on the experience of this neuron.