Nature Communications (Mar 2019)
Aedes mosquitoes acquire and transmit Zika virus by breeding in contaminated aquatic environments
- Senyan Du,
- Yang Liu,
- Jianying Liu,
- Jie Zhao,
- Clara Champagne,
- Liangqin Tong,
- Renli Zhang,
- Fuchun Zhang,
- Cheng-Feng Qin,
- Ping Ma,
- Chun-Hong Chen,
- Guodong Liang,
- Qiyong Liu,
- Pei-Yong Shi,
- Bernard Cazelles,
- Penghua Wang,
- Huaiyu Tian,
- Gong Cheng
Affiliations
- Senyan Du
- Tsinghua-Peking Joint Center for Life Sciences, School of Medicine, Tsinghua University
- Yang Liu
- Tsinghua-Peking Joint Center for Life Sciences, School of Medicine, Tsinghua University
- Jianying Liu
- Tsinghua-Peking Joint Center for Life Sciences, School of Medicine, Tsinghua University
- Jie Zhao
- Tsinghua-Peking Joint Center for Life Sciences, School of Medicine, Tsinghua University
- Clara Champagne
- IBENS, UMR 8197 CNRS-ENS Ecole Normale Supérieure
- Liangqin Tong
- Tsinghua-Peking Joint Center for Life Sciences, School of Medicine, Tsinghua University
- Renli Zhang
- Institute of Pathogenic Organisms, Shenzhen Center for Disease Control and Prevention
- Fuchun Zhang
- Institute of infectious diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University
- Cheng-Feng Qin
- State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology
- Ping Ma
- Department of Clinical Laboratory, Tsinghua University Hospital
- Chun-Hong Chen
- National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan
- Guodong Liang
- State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Viral Disease Control and Prevention, China CDC
- Qiyong Liu
- State Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, China CDC
- Pei-Yong Shi
- Department of Biochemistry and Molecular Biology, Department of Pharmacology and Toxicology, and Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch
- Bernard Cazelles
- IBENS, UMR 8197 CNRS-ENS Ecole Normale Supérieure
- Penghua Wang
- Department of Immunology, School of Medicine, the University of Connecticut Health Center
- Huaiyu Tian
- State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University
- Gong Cheng
- Tsinghua-Peking Joint Center for Life Sciences, School of Medicine, Tsinghua University
- DOI
- https://doi.org/10.1038/s41467-019-09256-0
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 11
Abstract
Here the authors show that Aedes mosquitoes can acquire ZIKV by breeding in contaminated aquatic systems, and that these infected mosquitoes can transmit ZIKV to susceptible mice. This suggests that human urine containing aquatic environments could contribute to ZIKV transmission.
