Eco-friendly Ag-CuO nanoparticles for antidiabetic, antimicrobial, anti-cancer, platelet aggregation inducing, antioxidant and photocatalytic applications

Abstract

The development of nanotechnology has a major impact on pharmaceutical sciences, dramatically improving diagnosis and treatment of many diseases that are life-threatening. A number of metallic nanoparticles are widely employed as nanomedicines because they may have medicinal applications. The environmental pollution from textile industry is one the big global problems that pose substantial risks to the environment and public health. Finding affordable, efficient, and sustainable technology to solve the challenges with pollution is crucial. In the present study we developed multi-functional Ag-doped CuO nanoparticles by utilizing Actinidia delicia extract by employing solution combustion method. The synthesized nanoparticles were examined by Transmission electron microscopy, scanning electron microscopy including energy dispersion X-ray analysis (EDX), X-ray diffraction (XRD), Fourier transform infrared spectroscopy, and UV–visible spectroscopy. The synthesized nanoparticles have a variety of applications including anticancer, antibacterial, and antidiabetic agents via modulating the activities of carbohydrate digesting enzymes, and they also exhibit effective photocatalytic activity by degrading the methylene blue dye. Platelet aggregation and plasma coagulation were both enhanced by Ag-doped copper oxide nanoparticles, and this was achieved without any noticeable haemolytic activity. This study presents an eco-friendly method for producing multifunctional Ag-CuO nanoparticles.

Keywords

• CuO nanoparticles
• Actinidia deliciosa
• Photocatalytic activity
• Anticancer
• Antidiabetic
• Antioxidant and antibacterial agent