<i>In Situ</i>
Visualization of the pKM101-Encoded Type IV Secretion System Reveals a Highly Symmetric ATPase Energy Center

Pratick Khara; Liqiang Song; Peter J. Christie; Bo Hu

doi:10.1128/mBio.02465-21

mBio (Oct 2021)

<i>In Situ</i> Visualization of the pKM101-Encoded Type IV Secretion System Reveals a Highly Symmetric ATPase Energy Center

Pratick Khara,
Liqiang Song,
Peter J. Christie,
Bo Hu

Affiliations

Pratick Khara: Department of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA
Liqiang Song: Department of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA
Peter J. Christie: ORCiD; Department of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA
Bo Hu: Department of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA

DOI: https://doi.org/10.1128/mBio.02465-21
Journal volume & issue: Vol. 12, no. 5

Abstract

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Bacterial type IV secretion systems (T4SSs) play central roles in antibiotic resistance spread and virulence. By cryo-electron tomography (CryoET), we solved the structure of the plasmid pKM101-encoded T4SS in the native context of the bacterial cell envelope.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal