Frontiers in Pediatrics (Feb 2022)

A Case Report of a 3-Year-Old Child With Anaphylactic Shock After a Diclofenac Suppository Confirmed by Serial Tryptase and a Basophil Activation Test

  • Wun-Yan Huang,
  • Wun-Yan Huang,
  • Tsu-Man Chiu,
  • Tsu-Man Chiu,
  • Su-Feng Kuo,
  • Wen-Hung Chung,
  • Yi-Giien Tsai,
  • Yi-Giien Tsai,
  • Yi-Giien Tsai

DOI
https://doi.org/10.3389/fped.2021.802715
Journal volume & issue
Vol. 9

Abstract

Read online

Diclofenac is one of the most commonly used non-steroidal anti-inflammatory drug (NSAID) agents for fever management by general practitioners. Anaphylaxis due to suppository of diclofenac sodium (Voltaren) is extremely rare in children. We report the case of a 3-year-old girl with anaphylactic shock after a diclofenac suppository with confirmation by serial tryptase and a basophil activation test.

Keywords