Rare case of acute renal failure secondary to Erdheim-Chester disease

Abstract

In this report we describe the clinical journey of a 62-year-old male that presented with acute kidney injury secondary to Erdheim-Chester disease, a non-Langerhans variant of histiocytosis rarely encountered by urological surgeons. ECD can uncommonly cause acute renal failure and management includes decompression of the collecting system. A multi-disciplinary approach is required to facilitate adequate investigation to determine the specific ECD subtype and most appropriate treatment options, particularly as the available targeted therapies have only recently been utilised.

Keywords

• Erdheim-Chester disease
• Non-langerhans histiocytosis
• Renal failure
• Renal manifestation