Primary yolk sac tumor of the gluteus: a case report and literature review

Abstract

Bo Li,1 Qianqian Jiang,1 Shitai Zhang,1 Yang Zhou,1 Qing-Fu Zhang,2 Ling OuYang1 1Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, 2Department of Pathology, the First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang, People’s Republic of China Abstract: Yolk sac tumor (YST) is a common malignant primitive germ cell tumor that often exhibits differentiation into endodermal structures. They most commonly occur in childhood and adolescence and are rare after the age of 40 years. Derived from the yolk sac during the embryonic period, YSTs can occur in the gonads and germ cells because the tumor cells migrate from the yolk sac toward the gonads. Here, we present a rare case of primary gluteus YST in a 3-year-old girl. She received BEP chemotherapy (bleomycin + etoposide + cisplatin) after surgical resection. There was no evidence of recurrence 7 months after primary treatment. Keywords: immunohistochemistry, yolk sac tumor, germ cell tumor

Keywords

• immunohistochemistry. yolk sac tumour. germ cell tumor