Serum Antioxidant Status to Assess Oxidative Stress in Brucella Infected Buffaloes

Abstract

The investigation was carried out to assess oxidative stress on the basis of serum antioxidant status in the buffaloes of Murrah breed having brucellosis. For this serum antioxidants like vitamin A, vitamin C, vitamin E and glutathione and various enzymes like catalase, superoxide dismutase, glutathione reductase and xanthine oxidase were determined. Results indicated that vitamin A, vitamin C, vitamin E and glutathione levels decreased significantly (p≤0.05) in affected buffaloes as compared to healthy buffaloes. Serum catalase, superoxide dismutase, glutathione reductase and xanthine oxidase activities increased significantly(p≤0.05) in affected buffaloes as compared to healthy buffaloes. Results indicated that the antioxidant status was altered in the brucella infected buffaloes. Depletion of levels of antioxidants in the serum reflected towards the development of oxidative stress in buffaloes having brucellosis.

Keywords

• Antioxidants
• brucellosis
• buffalo
• oxidative stress