Synthesis of (<i>+</i>)<i>-</i>(<i>R</i>)-Tiruchanduramine

Abstract

The absolute stereochemistry of the marine alkaloid (+)-(R)-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5% overall yield from Fmoc-D-Dab(Boc)-OH.

Keywords

• <i>Synoicum macroglossum</i>
• tiruchanduramine
• β-carboline
• guanidines