Diabetes and SARS-CoV-2 Infection: The Potential Role of Antidiabetic Therapy in the Evolution of COVID-19

Biagio Pinchera; Nicola Schiano Moriello; Antonio Riccardo Buonomo; Isabella Di Filippo; Anastasia Tanzillo; Giorgio Buzzo; Riccardo Villari; Ivan Gentile; Federico II COVID Team

doi:10.3390/microorganisms11010145

Microorganisms (Jan 2023)

Diabetes and SARS-CoV-2 Infection: The Potential Role of Antidiabetic Therapy in the Evolution of COVID-19

Biagio Pinchera,
Nicola Schiano Moriello,
Antonio Riccardo Buonomo,
Isabella Di Filippo,
Anastasia Tanzillo,
Giorgio Buzzo,
Riccardo Villari,
Ivan Gentile,
Federico II COVID Team

Affiliations

Biagio Pinchera: Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
Nicola Schiano Moriello: Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
Antonio Riccardo Buonomo: Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
Isabella Di Filippo: Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
Anastasia Tanzillo: Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
Giorgio Buzzo: Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
Riccardo Villari: Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
Ivan Gentile: Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
Federico II COVID Team: Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy

DOI: https://doi.org/10.3390/microorganisms11010145
Journal volume & issue: Vol. 11, no. 1
p. 145

Abstract

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Diabetes mellitus represents one of the most frequent comorbidities among patients with COVID-19, constituting a risk factor for a more severe prognosis than that of non-diabetic patients. However, the pathophysiological mechanism underlying this unfavorable outcome is still not completely clear. The goal of our study was to evaluate the potential role of antidiabetic therapy in the evolution of COVID-19.

Published in Microorganisms

ISSN: 2076-2607 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: https://www.mdpi.com/journal/microorganisms

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Abstract

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