Бюллетень сибирской медицины (Apr 2012)

Prognostic markers of urinary bladder cancer lymphatic spread

  • V. N. Pavlov,
  • A. A. Izmailov,
  • S. M. Izmailova,
  • T. V. Viktorova,
  • M. F. Urmantsev

DOI
https://doi.org/10.20538/1682-0363-2012-2-128-132
Journal volume & issue
Vol. 11, no. 2
pp. 128 – 132

Abstract

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Treatment results (2005—2009) for patients with invasive (N=104) urinary bladder carcinoma were analyzed. Molecular genetic analysis of cytochrome gene P450 polymorphous locus carried out: CYP1А1 (A2455G), СYP1A2 (T-2464delT), Glutathione S-transferase: GSTM1 (del), GSTP1 (A313G); DNA reparation: XRCC1 (G28152A) for patients with invasive urine bladder carcinoma with and without lymphogenic metastases was carried out. Genotypes associated with lyphogenic metastasis risk were identified.

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