Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review

Prakriti Singh Shrestha; Angela Ishak; Arun R. Napit; Sarosh Sarwar; Niraj Rai; Zoha Nizami; Niharika Bheemisetty; Prashanth Jayaraj; Amardeep Shrestha; Ivan D. Rodriguez

IDCases (Jan 2022)

Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review

Prakriti Singh Shrestha,
Angela Ishak,
Arun R. Napit,
Sarosh Sarwar,
Niraj Rai,
Zoha Nizami,
Niharika Bheemisetty,
Prashanth Jayaraj,
Amardeep Shrestha,
Ivan D. Rodriguez

Affiliations

Prakriti Singh Shrestha: Department of Research and Academic Affairs, Larkin Community Hospital, South Miami, FL, USA; Family Medical Clinic, O’Fallon, IL, USA; Corresponding author at: Department of Research and Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Angela Ishak: Department of Research and Academic Affairs, Larkin Community Hospital, South Miami, FL, USA
Arun R. Napit: Valley Health and Research Center, Srijananagar, Bhaktapur, Nepal
Sarosh Sarwar: Fazaia Medical College, Islamabad, Pakistan
Niraj Rai: University of Health Sciences, Lahore, Pakistan
Zoha Nizami: Department of Research and Academic Affairs, Larkin Community Hospital, South Miami, FL, USA
Niharika Bheemisetty: Department of Research and Academic Affairs, Larkin Community Hospital, South Miami, FL, USA
Prashanth Jayaraj: Department of Family Medicine, Larkin Community Hospital, South Miami, FL, USA
Amardeep Shrestha: Family Medical Clinic, O’Fallon, IL, USA
Ivan D. Rodriguez: Department of Family Medicine, Larkin Community Hospital, South Miami, FL, USA

Journal volume & issue: Vol. 29
p. e01582

Abstract

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Thrombosis following COVID-19 vaccination commonly occurs with vector-based vaccines. The proposed mechanism is vaccine-induced thrombotic thrombocytopenia (VITT), with thrombocytopenia as principal manifestation. We present a 51-year-old male who came with isolated portal vein thrombosis (PVT) one day after Moderna vaccination, without associated thrombocytopenia, challenging VITT as being the only patho-mechanism. Further exploration of these possible alternative mechanisms is needed for COVID-19 vaccine-related thrombotic complications.

Published in IDCases

ISSN: 2214-2509 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: http://www.journals.elsevier.com/idcases/

About the journal

Abstract

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