Nature Communications (Feb 2021)

Droplet printing reveals the importance of micron-scale structure for bacterial ecology

  • Ravinash Krishna Kumar,
  • Thomas A. Meiller-Legrand,
  • Alessandro Alcinesio,
  • Diego Gonzalez,
  • Despoina A. I. Mavridou,
  • Oliver J. Meacock,
  • William P. J. Smith,
  • Linna Zhou,
  • Wook Kim,
  • Gökçe Su Pulcu,
  • Hagan Bayley,
  • Kevin R. Foster

DOI
https://doi.org/10.1038/s41467-021-20996-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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The spatial arrangement of bacterial strains and species within microbial communities is considered crucial for their ecology. Here, Krishna Kumar et al. use a droplet-based printing method to arrange different bacterial genotypes across a sub-millimetre array, and show that micron-scale changes in spatial distributions can drive major shifts in ecology.