PLoS ONE (Jan 2012)

Avian influenza H9N2 seroprevalence among poultry workers in Pune, India, 2010.

  • Shailesh D Pawar,
  • Babasaheb V Tandale,
  • Chandrashekhar G Raut,
  • Saurabh S Parkhi,
  • Tanaji D Barde,
  • Yogesh K Gurav,
  • Sadhana S Kode,
  • Akhilesh C Mishra

DOI
https://doi.org/10.1371/journal.pone.0036374
Journal volume & issue
Vol. 7, no. 5
p. e36374

Abstract

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Avian influenza (AI) H9N2 has been reported from poultry in India. A seroepidemiological study was undertaken among poultry workers to understand the prevalence of antibodies against AI H9N2 in Pune, Maharashtra, India. A total of 338 poultry workers were sampled. Serum samples were tested for presence of antibodies against AI H9N2 virus by hemagglutination inhibition (HI) and microneutralization (MN) assays. A total of 249 baseline sera from general population from Pune were tested for antibodies against AI H9N2 and were negative by HI assay using ≥40 cut-off antibody titre. Overall 21 subjects (21/338 = 6.2%) were positive for antibodies against AI H9N2 by either HI or MN assays using ≥40 cut-off antibody titre. A total of 4.7% and 3.8% poultry workers were positive for antibodies against AI H9N2 by HI and MN assay respectively using 40 as cut-off antibody titre. This is the first report of seroprevalence of antibodies against AI H9N2 among poultry workers in India.