Medical Mycology Case Reports (Sep 2015)

Scedosporium apiosermum infection of the “Native” valve: Fungal endocarditis in an orthotopic heart transplant recipient

  • Meredith E. Clement,
  • Eileen K. Maziarz,
  • Jacob N. Schroder,
  • Chetan B. Patel,
  • John R. Perfect

DOI
https://doi.org/10.1016/j.mmcr.2015.07.005
Journal volume & issue
Vol. 9, no. C
pp. 34 – 36

Abstract

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Scedosporium apiospermum is an increasingly appreciated pathogen in immunosuppressed patients. We present a case of S. apiospermum endocarditis in a 70-year-old male who had undergone orthotopic heart transplant. Echocardiogram demonstrated a 1.4 cm tricuspid valve vegetation. He underwent valve replacement, complicated by fatal massive post-operative haemorrhage. Valve cultures grew S. apiospermum. To our knowledge, our case is the first reported instance of endocarditis caused by S. apiospermum in a recipient of a cardiac transplant.

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