P104: BASE EDITING REPAIRS THE HBE MUTATION RESTORING THE PRODUCTION OF NORMAL GLOBIN CHAINS IN SEVERE HBE/β-THALASSEMIA PATIENT HEMATOPOIETIC STEM AND ERYTHROID CELLS
M Badat,
P Hua,
S Mettananda,
C Fisher,
N Roy,
S Rice,
A Roy,
D Higgs,
J Davies
Affiliations
M Badat
1 Barts Health NHS Trust, London, UNITED KINGDOM
P Hua
2 Weatherall Institute of Molecular Medicine, Oxford, UNITED KINGDOM
S Mettananda
3 University of Kelaniya, Ragama, SRI LANKA
C Fisher
2 Weatherall Institute of Molecular Medicine, Oxford, UNITED KINGDOM
N Roy
4 Dept Haematology, Oxford University Hospitals NHS Trust, Oxford, UNITED KINGDOM
S Rice
2 Weatherall Institute of Molecular Medicine, Oxford, UNITED KINGDOM
A Roy
2 Weatherall Institute of Molecular Medicine, Oxford, UNITED KINGDOM
D Higgs
2 Weatherall Institute of Molecular Medicine, Oxford, UNITED KINGDOM
J Davies
2 Weatherall Institute of Molecular Medicine, Oxford, UNITED KINGDOM