Data from quantitative serum proteomic analysis after laparoscopic gastric plication

Parisa Savedoroudi; Tue Bjerg Bennike; Kenneth Kastaniegaard; Mohammad Talebpour; Alireza Ghassempour; Allan Stensballe

Data in Brief (Aug 2019)

Data from quantitative serum proteomic analysis after laparoscopic gastric plication

Parisa Savedoroudi,
Tue Bjerg Bennike,
Kenneth Kastaniegaard,
Mohammad Talebpour,
Alireza Ghassempour,
Allan Stensballe

Affiliations

Parisa Savedoroudi: Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran; Department of Health Science and Technology, Aalborg University, Denmark
Tue Bjerg Bennike: Department of Health Science and Technology, Aalborg University, Denmark
Kenneth Kastaniegaard: Department of Health Science and Technology, Aalborg University, Denmark
Mohammad Talebpour: Laparoscopic Surgery Ward, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran; Corresponding author. Head of Laparoscopic Ward, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Alireza Ghassempour: Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran; Corresponding author. Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G.C., P.O. Box 19835-389, Evin, Tehran, Iran.
Allan Stensballe: Department of Health Science and Technology, Aalborg University, Denmark; Corresponding author. Department of Health Science and Technology, Fredrik Bajers Vej 7, E4-114 9220, Aalborg, Denmark.

Journal volume & issue: Vol. 25

Abstract

Read online

Bariatric surgery is an effective treatment for morbid obesity with a sustained weight loss and improvements in metabolic syndrome. We present a label free quantitative shotgun proteomics approach to analyze the serum proteome of obese people who underwent Laparoscopic Gastric Plication (LGP) as a new bariatric surgery. Pre-surgery serum samples of obese individuals were compared with the serum of the same subjects 1–2 months post-surgery (T1) and 4–5 months post-surgery (T2). The data provide a list of 224 quantifiable proteins with at least two unique peptides that were quantifiable in at least 70% of samples. Gene ontology biological processes and molecular functions of differentially regulated proteins between pre- and post-surgery samples were investigated using WebGestalt online tool. In addition, molecular networks of differentially abundant proteins were determined through Ingenuity Pathway Analysis (IPA) software. This report is related to the research article entitled “Serum proteome changes and accelerated reduction of fat mass after Laparoscopic Gastric Plication in morbidly obese patients” (Savedoroudi et al. [1]). Proteomics data have been deposited to the ProteomeXchange Consortium (http://proteomecentral.proteomexchange.org) via the PRIDE partner repository through the identifier PXD010528. Keywords: Bariatric surgery, Laparoscopic gastric plication, Obesity, Proteomics

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

About the journal