Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection

Robert Thänert; Oliver Goldmann; Andreas Beineke; Eva Medina

doi:10.1038/ncomms14268

Nature Communications (Feb 2017)

Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection

Robert Thänert,
Oliver Goldmann,
Andreas Beineke,
Eva Medina

Affiliations

Robert Thänert: Infection Immunology Research Group, Helmholtz Centre for Infection Research
Oliver Goldmann: Infection Immunology Research Group, Helmholtz Centre for Infection Research
Andreas Beineke: Institute for Pathology, University of Veterinary Medicine Hannover
Eva Medina: Infection Immunology Research Group, Helmholtz Centre for Infection Research

DOI: https://doi.org/10.1038/ncomms14268
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 13

Abstract

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Drugs inhibiting virulence factors of bacterial pathogens are under development. Here, Thänertet al. analyse the transcriptomes of host and pathogen during Staphylococcus aureusinfection of two mouse strains, and show that virulence determinants are differentially expressed in different mouse strains.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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