Non-Hodgkin′s lymphoma: A rare diagnosis on cervicovaginal cytology

Abstract

Cervicovaginal smear screening is well known to reduce morbidity and mortality rates of invasive cervical carcinoma. Herein, we report a case of 56-year-old woman whose cervicovaginal smear was found to consist of malignant cells characterized by high nuclear/cytoplasmic ratio, scant rim of cytoplasm, coarsely granular nuclear chromatin and irregular nuclear membrane that were all reminiscent of a malignant lymphoma. Histopathological examination of the hysterectomy and unilateral adnexectomy specimen confirmed the presence of a diffuse large B-cell non Hodgkin′s lymphoma involving the cervix, endometrium, myometrium, serosa and the right ovary.

Keywords

• Cervicovaginal smear; extranodal; malignant lymphoma