Vitamin D receptor polymorphisms and vitamin D insufficiency are not associated with sepsis in critically ill children: a case-control study

Abstract

Highlights • Vitamin D level was low in both pediatric septic ICU patients and age- and sex-matched healthy controls. • Vitamin D levels were unaffected by VDR polymorphisms, and their distribution was similar in both groups. • Neither the need for mechanical ventilation or inotropic treatment nor the sepsis outcome was impacted by vitamin D or VDR polymorphisms.

Keywords

• Pediatric
• Polymorphisms
• Sepsis
• VDR
• Vitamin D