Ameloblastomatous calcifying odontogenic cyst: A rare histologic variant

Abstract

Ameloblastoma is a well-known odontogenic tumor that can be associated with calcifying odontogenic cysts (COCs), but only a few reports give its clinical and radiographic features. Calcifying odontogenic cyst was first categorized as a distinct entity by Gorlin et al., and has been named after him since then. Calcifying odontogenic cyst is an uncommon developmental odontogenic lesion that demonstrates histopathologic diversity. It is well known that this lesion can occur in association with odontogenic tumors such as complex odontoma and ameloblastoma. The term COC was not included by the World Health Organization (WHO) in its report of 2005 and is called calcifying cystic odontogenic tumor (CCOT). Histopathologic examination of ameloblastomatous CCOT reveals ameloblastic islands containing ghost cells. Although association of ameloblastoma with this lesion is important, only a few cases have been reported in literature. The present case report is of ameloblastomatous calcifying cystic odontogenic tumor, a rare histologic variant, in a 20-year-old male patient in the left mandibular posterior region.

Keywords

• Ameloblastomatous COC
• calcifying cystic odontogenic tumor
• calcifying epithelial odontogenic cyst
• ghost cells