Frontiers in Oncology (Nov 2020)

Synthesis of Recommendations From 25 Countries and 31 Oncology Societies: How to Navigate Through Covid-19 Labyrinth

  • Konstantinos Kamposioras,
  • Davide Mauri,
  • Konstantinos Papadimitriou,
  • Alan Anthoney,
  • Nadia Hindi,
  • Nadia Hindi,
  • Branka Petricevic,
  • Mario Dambrosio,
  • Antonis Valachis,
  • Pantelis Kountourakis,
  • Jindrich Kopecky,
  • Cvetka Grašič Kuhar,
  • Lazar Popovic,
  • Nataliya P. Chilingirova,
  • Nataliya P. Chilingirova,
  • George Zarkavelis,
  • Ramon Andrade de Mello,
  • Ramon Andrade de Mello,
  • Natalija Dedić Plavetić,
  • Christos Christopoulos,
  • Bianca Mostert,
  • John R. Goffin,
  • Dimitiros Tzachanis,
  • Haytham Hamed Saraireh,
  • Fei Ma,
  • Ida Pavese,
  • Maria Tolia

DOI
https://doi.org/10.3389/fonc.2020.575148
Journal volume & issue
Vol. 10

Abstract

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IntroductionPandemic COVID-19 is an unexpected challenge for the oncological community, indicating potential detrimental effects on cancer patients. Our aim was to summarize the converging key points providing a general guidance in order to support decision making, pertaining to the oncologic care in the middle of a global outbreak.MethodsWe did an international online search in twenty five countries that have managed a surge in cancer patient numbers. We collected the recommendations from thirty one medical oncology societies.ResultsBy synthesizing guidelines for a) oncology service delivery adjustments, b) general and specific treatment adaptations, and c) discrepancies from guidelines comparison, we present a clinical synopsis with the forty more crucial statements. A Covid-19 risk stratification base was also created in order to obtain a quick, objective patient assessment and a risk-benefit evaluation on a case-by-case basis.ConclusionsIn an attempt to face these complex needs and due to limited understanding of COVID-19, a variability of recommendations based on general epidemiological and infectious disease principles rather than definite cancer-related evidence has evolved. Additionally, the absence of an effective treatment or vaccine requires the development of cancer management guidance, capitalizing on comprehensive COVID-19 oncology experience globally.

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