Micromachines (Feb 2023)

Fabrication and Assembly Techniques for Sub-mm Battery-Free Epicortical Implants

  • Adam Khalifa,
  • Mehdi Nasrollahpour,
  • Ali Nezaratizadeh,
  • Xiao Sha,
  • Milutin Stanaćević,
  • Nian X. Sun,
  • Sydney S. Cash

DOI
https://doi.org/10.3390/mi14020476
Journal volume & issue
Vol. 14, no. 2
p. 476

Abstract

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Over the past three decades, we have seen significant advances in the field of wireless implantable medical devices (IMDs) that can interact with the nervous system. To further improve the stability, safety, and distribution of these interfaces, a new class of implantable devices is being developed: single-channel, sub-mm scale, and wireless microelectronic devices. In this research, we describe a new and simple technique for fabricating and assembling a sub-mm, wirelessly powered stimulating implant. The implant consists of an ASIC measuring 900 × 450 × 80 µm3, two PEDOT-coated microelectrodes, an SMD inductor, and a SU-8 coating. The microelectrodes and SMD are directly mounted onto the ASIC. The ultra-small device is powered using electromagnetic (EM) waves in the near-field using a two-coil inductive link and demonstrates a maximum achievable power transfer efficiency (PTE) of 0.17% in the air with a coil separation of 0.5 cm. In vivo experiments conducted on an anesthetized rat verified the efficiency of stimulation.

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