DHA/AA alleviates LPS-induced Kupffer cells pyroptosis via GPR120 interaction with NLRP3 to inhibit inflammasome complexes assembly

Affiliations

Guoqiang Fan: MOE Joint International Research Laboratory of Animal Health and Food Safety, Nanjing Agricultural University
Yanfei Li: MOE Joint International Research Laboratory of Animal Health and Food Safety, Nanjing Agricultural University
Jinglong Chen: MOE Joint International Research Laboratory of Animal Health and Food Safety, Nanjing Agricultural University
Yibo Zong: MOE Joint International Research Laboratory of Animal Health and Food Safety, Nanjing Agricultural University
Xiaojing Yang: MOE Joint International Research Laboratory of Animal Health and Food Safety, Nanjing Agricultural University

Abstract

DHA/AA alleviated LPS-induced Kupffer cells pyroptosis via GPR120 interaction with NLRP3 to inhibit NLRP3 inflammasome assembly.