Clonal expansion of CAR T cells harboring lentivector integration in the CBL gene following anti-CD22 CAR T-cell therapy

• Nirali N. Shah,
• Haiying Qin,
• Bonnie Yates,
• Ling Su,
• Haneen Shalabi,
• Mark Raffeld,
• Mark A. Ahlman,
• Maryalice Stetler-Stevenson,
• Constance Yuan,
• Shuang Guo,
• Siyuan Liu,
• Stephen H. Hughes,
• Terry J. Fry,
• Xiaolin Wu

Affiliations

Nirali N. Shah

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD; Nirali N. Shah, National Institutes of Health, Building 10/CRC, Room 1-5750, 10 Center Dr, Bethesda, MD 20892

Haiying Qin

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD

Bonnie Yates

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD

Ling Su

Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD

Haneen Shalabi

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD

Mark Raffeld

Molecular Diagnostics Section, Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD

Mark A. Ahlman

Radiology and Imaging Sciences, NIH Clinical Center, Bethesda, MD

Maryalice Stetler-Stevenson

Flow Cytometry, Department of Pathology, NCI, NIH, Bethesda, MD

Constance Yuan

Flow Cytometry, Department of Pathology, NCI, NIH, Bethesda, MD

Shuang Guo

Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD

Siyuan Liu

Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD

Stephen H. Hughes

HIV Dynamics and Replication Program, NCI, NIH, Frederick, MD

Terry J. Fry

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO; Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, CO

Xiaolin Wu

Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD