Primary Breast Sarcoma: A Diagnostic Conundrum

Abstract

Primary breast sarcomas are rare constituting <1% of all breast malignancies. These histologically heterogeneous non-epithelial aggressive neoplasm arises from the connective tissue within the breast and have a high tendency of recurrence even after excisional biopsy. Therefore, it necessitates a multidisciplinary approach to modify the overall prognosis and mortality. To throw light on this entity, we here report a few cases that presented as huge lumps in the breast and were missed in fine needle aspiration cytology. Each case was followed by modified radical mastectomy and was diagnosed as sarcoma of the breast confirmed by immunohistochemistry without any history of previous breast disease and radiation Keywords: Sarcoma, Diagnosis, Fine Needle Aspiration Cytology, Immunohistochemistry