Reactive oxygen species lead to age-related bone loss by accelerating senescence of osteoblasts in mice

• Jan-Moritz Ramge,
• Chen Xiangxu,
• Verena Fischer,
• Melanie Haffner-Luntzer,
• Jan Tuckermann,
• Karin Scharfetter-Kochanek,
• Anita Ignatius,
• Astrid Liedert

Affiliations

Jan-Moritz Ramge

Institute of Orthopeadic Research and Biomechanics, University Hospital Ulm, Ulm, Germany; Corresponding author.

Chen Xiangxu

Institute of Orthopeadic Research and Biomechanics, University Hospital Ulm, Ulm, Germany

Verena Fischer

Institute of Orthopeadic Research and Biomechanics, University Hospital Ulm, Ulm, Germany

Melanie Haffner-Luntzer

Institute of Orthopeadic Research and Biomechanics, University Hospital Ulm, Ulm, Germany

Jan Tuckermann

Institute of Comparative Molecular Endocrinology, University Ulm, Ulm, Germany

Karin Scharfetter-Kochanek

Institute of Dermatology and Allergic Diseases, University Hospital Ulm, Ulm, Germany

Anita Ignatius

Institute of Orthopeadic Research and Biomechanics, University Hospital Ulm, Ulm, Germany

Astrid Liedert

Institute of Orthopeadic Research and Biomechanics, University Hospital Ulm, Ulm, Germany