Медицинский вестник Юга России (Jun 2010)
Algorithm of Hepatitis B Vaccinal Prevention at Children with Acute Lymphoblastic Leukemia in Dynamics of Program Therapy
Abstract
Purpose: To create the algorithm of hepatitis B vaccinal prevention at children with acute lymphoblastic leukemia. Materials and Methods: The data of 181 children with acute lymphoblastic leukemia, from which 99 patients received specific hepatitis B prevention with vaccine «Engerix B», have been investigated. The authors have assessed correlations between efficiency of offered vaccinal prevention and leuco/neutropenia degrees at patients in days of vaccinations. The analysis of hepatitis B infect level at stages of vaccination was carried out. Results: The algorithm of hepatitis B vaccinal prevention at children with acute lymphoblastic leukemia is offered.