New β-ketophosphonates for the Synthesis of Prostaglandin Analogues. 1. Phosphonates with a Bicyclo[3.3.0]octene Scaffold Spaced by a Methylene Group from the β-ketone

Abstract

The modifications of the ω-side chain have led to the most interesting biological activities of the prostaglandin analogues [...]

Keywords

• mono and bis β-ketophosphonates
• bicyclo[3.3.0]octene
• prostaglandin analogues