Quality of life of patients with low back pain and pharmacoeconomic aspects of the treatment

Abstract

Objective. To define clinical efficacy of diclofenac and nise in pts with low back pain (LBP) considering quality of life (QL) and pharmacoeconomic aspects (PA) Material and methods . 100 pts with chronic LBP due to vertebral osteochondrosis were included. Clinical examination was performed. QL was assessed with 4 questionnaires: Health Assessment Questionnaire (HAQ), WOMAC osteoarthritis index (Vfersion vas. 1), Osvestry Low Back Pain Disability Questionnaire and SF-36. 50 pts of the 1 group received diclofenac retard 100 mg twice a day during 10 days. Nise was administered to the 50 pts of the 2 group 100 mg twice a day. All pts received midocalm 450 mg/day. Results. The study showed high efficacy of nise in complex treatment of pts with chronic LBP considering its analgesic and anti-inflammatory properties, low adverse events frequency so as PA and QL improvement.

Keywords

• back pain
• nise
• dicioifenac
• efficacy
• safety
• quality of life