Frontiers in Cardiovascular Medicine (Jan 2023)

Case report: Metastatic myxoid liposarcoma arising from the right atrium extends as cardiac tamponade—A rare case of atrial oncology

  • Muralidharan Thoddi Ramamurthy,
  • Vinod Kumar Balakrishnan,
  • Sini Sunny,
  • Abinayaa Rajkumar,
  • Sandhya Sundaram,
  • Preetam Krishnamurthy,
  • Nagendra Boopathy Senguttuvan,
  • Arunan Murali,
  • J. D. Roy Santhosham,
  • Kalaiselvi Periandavan,
  • Namakkal S. Rajasekaran,
  • Namakkal S. Rajasekaran

DOI
https://doi.org/10.3389/fcvm.2022.1046436
Journal volume & issue
Vol. 9

Abstract

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The reported incidence of liposarcomas in ~2,000 cases annually results in about 30% of myxoid liposarcomas. Cardiac myoxid liposarcomas are very rare; their presentation could be cardiac tamponade, due to direct compression of the tumor and/or pericardial effusion. In this report, we describe a patient who presented with pericardial effusion secondary to myoxid liposarcomas from the right atrium, an extremely rare presentation of liposarcomas in the heart. We also present non-invasive imaging through echocardiography, CECT thorax and FDG PET scans, followed by a CT-guided mass biopsy. Histopathology of the right atrial mass demonstrated myxoid liposarcoma positive for the S100 tumor marker.

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