Pakistan Journal of Medicine and Dentistry (May 2024)
An Unusual Presentation of Autoimmune Pancreatitis in a Patient with Acute Pancreatitis and Obstructive Jaundice
Abstract
utoimmune pancreatitis is a rare fibroinflamatory disorder of the pancreas with immunoglobulin G 4(IgG4) associated systemic disease which is steroid responsive. 1,2 It has a variable clinical presentation ranging from obstructive jaundice, abdominal pain, steatorrhea and diabetes mellitus. In general presentation of autoimmune pancreatitis as acute pancreatitis is considered to be uncommon. The article presents a case of a 30 years old female newly diagnosed as diabetes mellitus presented with obstructive jaundice with raised lipase and amylase treated as acute pancreatitis. Due to persistent elevation of amylase and lipase and deranged liver function test she was further evaluated her CT findings were typical of autoimmune pancreatitis with raised serum IgG4 levels diagnosed as autoimmune pancreatitis. She was treated with steroids and responded well and after few months presented with relapse. Key Words: Autoimmune Pancreatitis, Obstructive Jaundice, Immunoglobulin IgG4, Acute Pancreatitis.