Entamoeba and Giardia parasites implicated as hosts of CRESS viruses

Cormac M. Kinsella; Aldert Bart; Martin Deijs; Patricia Broekhuizen; Joanna Kaczorowska; Maarten F. Jebbink; Tom van Gool; Matthew Cotten; Lia van der Hoek

doi:10.1038/s41467-020-18474-w

Nature Communications (Sep 2020)

Entamoeba and Giardia parasites implicated as hosts of CRESS viruses

Cormac M. Kinsella,
Aldert Bart,
Martin Deijs,
Patricia Broekhuizen,
Joanna Kaczorowska,
Maarten F. Jebbink,
Tom van Gool,
Matthew Cotten,
Lia van der Hoek

Affiliations

Cormac M. Kinsella: Laboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam
Aldert Bart: Laboratory of Clinical Parasitology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam
Martin Deijs: Laboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam
Patricia Broekhuizen: Laboratory of Clinical Parasitology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam
Joanna Kaczorowska: Laboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam
Maarten F. Jebbink: Laboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam
Tom van Gool: Laboratory of Clinical Parasitology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam
Matthew Cotten: MRC/UVRI & LSHTM Uganda Research Unit
Lia van der Hoek: Laboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam

DOI: https://doi.org/10.1038/s41467-020-18474-w
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 10

Abstract

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Metagenomics allows virus genome discovery, but the viral hosts are often not identified. Here, Kinsella et al. use recombination events between virus genomes, statistical association of viruses to hosts in clinical samples, and analysis of endogenous viral elements in host genomes to identify probable hosts of three CRESS virus families.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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