Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells

Abstract

The recent emergence of human infection with influenza A(H10N8) virus is an urgent public health concern. Genomic analysis showed that the virus was conserved in chicken eggs but presented substantial adaptive mutations in MDCK cells. Our results provide additional evidence for the avian origin of this influenza virus.

Keywords

• influenza A virus
• mutation
• genome
• avian-origin
• antiviral drug resistance
• viruses