Cellular Oncology (Jan 2010)
Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis
Abstract
Background: Two novel assays quantifying Epithelial to Mesenchymal Transition (EMT) were compared to traditional motility and migration assays. TGF-β1 treatment of AY-27 rat bladder cancer cells acted as a model of EMT in tumourigenesis.