Structures of the eukaryotic ribosome and its translational states in situ

Patrick C. Hoffmann; Jan Philipp Kreysing; Iskander Khusainov; Maarten W. Tuijtel; Sonja Welsch; Martin Beck

doi:10.1038/s41467-022-34997-w

Nature Communications (Dec 2022)

Structures of the eukaryotic ribosome and its translational states in situ

Patrick C. Hoffmann,
Jan Philipp Kreysing,
Iskander Khusainov,
Maarten W. Tuijtel,
Sonja Welsch,
Martin Beck

Affiliations

Patrick C. Hoffmann: Department of Molecular Sociology, Max Planck Institute of Biophysics
Jan Philipp Kreysing: Department of Molecular Sociology, Max Planck Institute of Biophysics
Iskander Khusainov: Department of Molecular Sociology, Max Planck Institute of Biophysics
Maarten W. Tuijtel: Department of Molecular Sociology, Max Planck Institute of Biophysics
Sonja Welsch: Central Electron Microscopy Facility, Max Planck Institute of Biophysics
Martin Beck: Department of Molecular Sociology, Max Planck Institute of Biophysics

DOI: https://doi.org/10.1038/s41467-022-34997-w
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 9

Abstract

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The translational states of eukaryotic ribosomes have so far been only investigated in vitro. Here, authors obtained the 3.8 Å in situ 80S ribosome structure, the distribution of translational states and unique arrangement of rRNA expansion segments.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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