PLoS ONE (Jan 2012)

Post-operative hypertension after total knee arthroplasty and the effects on transfusion rates.

  • Russell R Russo,
  • Vinod Dasa,
  • Robert Duarte,
  • Burton Beakley,
  • Manish Mishra,
  • Hilary Thompson

DOI
https://doi.org/10.1371/journal.pone.0050967
Journal volume & issue
Vol. 7, no. 12
p. e50967

Abstract

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Transfusions are a cause of significant patient morbidity as well as expense. Anesthesia literature has examined controlled intraoperative hypotension as a means for reducing blood loss and transfusions. Our hypothesis is that inversely increased blood pressure post-operatively would then lead to increased blood loss and transfusions.We examined 105 consecutive patients who underwent TKA. We found a significant odds ratio of 1.123 for pre-operative hematocrit. For post-operative blood pressure, we calculated an insignificant odds ratio of 1.007, proving no relationship between post-operative blood pressure and transfusions.This is the first study to examine increased post-operative blood pressure's contribution to transfusion rates. Although we confirmed that low pre-operative hematocrit contributes to increased transfusions, we did not find a relationship between post-operative blood pressure and transfusions.