A rare case of primary paratesticular adenocarcinoma presenting as cough

Abstract

Primary paratesticular adenocarcinoma is an extremely rare form of non-germ cell cancer. There are very few reports documented in the medical literature. It is notoriously challenging to diagnose and no treatment guidelines currently exist. Herein we present a case of a 45-year old male presenting with a chronic cough resulting from an underlying primary paratesticular adenocarcinoma. The patient was enrolled in a clinical trial for rare genitourinary cancers, known as the Iconic Trial. The following case report explores the immunopathologic characterization of this malignancy and describes the outcome from treatment for a single patient. In addition, a detailed review of the current medical literature is included.

Keywords

• Paratesticular neoplasms
• Genitourinary cancers
• Paratesticular adenocarcinoma
• Ipilimumab
• Cabozanitib and nivolumab