Molbank (Sep 2013)
6-[5-Chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridine
Abstract
Suzuki coupling reaction of 5-fluoro-6-methylpyridin-2-ylboronic acid (1) with 4-chloro-2-iodo-1-(trifluoromethyl)benzene (2) in the presence of dikis and K2CO3 produce C-C coupled new title compound 6-(5-chloro-2-(trifluoromethyl)phenyl)-3-fluoro-2-methylpyridine (3). The structure of the newly synthesized compound has been confirmed by IR, 1H-NMR, 13C-NMR, LC-MS and CHN analysis.
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