Poly(ethylene glycol)-Based Peptidomimetic “PEGtide” of Oligo-Arginine Allows for Efficient siRNA Transfection and Gene Inhibition

• Alan Hibbitts,
• Aoife M. O’Connor,
• Joanna McCarthy,
• Éanna B. Forde,
• Gary Hessman,
• Caitriona M. O’Driscoll,
• Sally-Ann Cryan,
• Marc Devocelle

Affiliations

Alan Hibbitts

†Tissue Engineering Research Group, Department of Anatomy, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland

Aoife M. O’Connor

‡Department of Chemistry, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland

Joanna McCarthy

Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland

Éanna B. Forde

‡Department of Chemistry, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland

Gary Hessman

⊥School of Chemistry, Trinity College Dublin (TCD), The University of Dublin, Dublin, Ireland

Caitriona M. O’Driscoll

Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland

Sally-Ann Cryan

†Tissue Engineering Research Group, Department of Anatomy, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland

Marc Devocelle

‡Department of Chemistry, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland