Inframammary Dermatitis: A Case of Localized Late-Onset Darier’s Disease

Abstract

Darier’s disease (DD) is an autosomal dominant inherited genodermatosis which is often under- or misdiagnosed. In the majority of cases, the disease manifests in adolescents or young adults with small brownish-yellow, warty, hyperkeratotic papules in multiple seborrheic areas of the body. Localized DD (LDD) is a clinical variant, first described by Kreibich in 1906; only a few cases are reported in the literature. We described the case of an aged woman presenting with LDD, and we review the literature on this subject.

Keywords

• Corticosteroids
• Darier-White disease
• Genodermatoses
• Retinoids
• Adapalene
• ATP2A2 gene