Real-time non-contact cellular imaging and angiography of human cornea and limbus with common-path full-field/SD OCT

Viacheslav Mazlin; Peng Xiao; Jules Scholler; Kristina Irsch; Kate Grieve; Mathias Fink; A. Claude Boccara

doi:10.1038/s41467-020-15792-x

Nature Communications (Apr 2020)

Real-time non-contact cellular imaging and angiography of human cornea and limbus with common-path full-field/SD OCT

Viacheslav Mazlin,
Peng Xiao,
Jules Scholler,
Kristina Irsch,
Kate Grieve,
Mathias Fink,
A. Claude Boccara

Affiliations

Viacheslav Mazlin: Institut Langevin, ESPCI Paris, PSL University, CNRS
Peng Xiao: Institut Langevin, ESPCI Paris, PSL University, CNRS
Jules Scholler: Institut Langevin, ESPCI Paris, PSL University, CNRS
Kristina Irsch: Vision Institute/CIC 1423, Sorbonne University, UMR_S 968/INSERM, U968/CNRS, UMR_7210
Kate Grieve: Vision Institute/CIC 1423, Sorbonne University, UMR_S 968/INSERM, U968/CNRS, UMR_7210
Mathias Fink: Institut Langevin, ESPCI Paris, PSL University, CNRS
A. Claude Boccara: Institut Langevin, ESPCI Paris, PSL University, CNRS

DOI: https://doi.org/10.1038/s41467-020-15792-x
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 14

Abstract

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Currently a cell-resolution map of the human cornea can only be obtained in the clinic with a confocal microscope in contact with the eye. Here the authors develop a full-field/spectral-domain OCT microscope (FF/SD OCT) to enable cell-level detail of the entire ocular surface, as well as blood flow and tear dynamics.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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