Double-headed nucleosides: Synthesis and applications

Abstract

Double-headed nucleoside monomers have immense applications for studying secondary nucleic acid structures. They are also well-known as antimicrobial agents. This review article accounts for the synthetic methodologies and the biological applications of double-headed nucleosides.

Keywords

• acyclic double-headed nucleosides
• bicyclic double-headed nucleosides
• furanosyl double-headed nucleosides
• modified nucleosides
• pyranosyl double-headed nucleosides