Circulating miRNome profiling data in Behçet's syndrome

Giacomo Bagni; Giacomo Emmi; Elena Lastraioli; Francesca Di Patti; Elena Silvestri; Angela Guerriero; Serena Pillozzi; Elena Niccolai; Amedeo Amedei; Lorenzo Emmi; Domenico Prisco; Annarosa Arcangeli

Data in Brief (Oct 2021)

Circulating miRNome profiling data in Behçet's syndrome

Giacomo Bagni,
Giacomo Emmi,
Elena Lastraioli,
Francesca Di Patti,
Elena Silvestri,
Angela Guerriero,
Serena Pillozzi,
Elena Niccolai,
Amedeo Amedei,
Lorenzo Emmi,
Domenico Prisco,
Annarosa Arcangeli

Affiliations

Giacomo Bagni: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Giacomo Emmi: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; SOD Interdisciplinary Internal Medicine-Behçet Center and Lupus Clinic–Azienda Ospedaliero Universitaria Careggi, Florence, Italy
Elena Lastraioli: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Francesca Di Patti: Department of Physics, University of Florence, Sesto Fiorentino, Florence, Italy; Center for the Study of Complex Dynamics (CSDC), Sesto Fiorentino, Florence, Italy
Elena Silvestri: SOD Interdisciplinary Internal Medicine-Behçet Center and Lupus Clinic–Azienda Ospedaliero Universitaria Careggi, Florence, Italy
Angela Guerriero: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Serena Pillozzi: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Elena Niccolai: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Amedeo Amedei: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; SOD Interdisciplinary Internal Medicine-Behçet Center and Lupus Clinic–Azienda Ospedaliero Universitaria Careggi, Florence, Italy
Lorenzo Emmi: Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy
Domenico Prisco: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Annarosa Arcangeli: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Center for the Study of Complex Dynamics (CSDC), Sesto Fiorentino, Florence, Italy; Corresponding author at: Department of Experimental and Clinical Medicine, University of Florence, Florence Italy.

Journal volume & issue: Vol. 38
p. 107435

Abstract

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We conducted a screening analysis to assess the presence of a characteristic extracellular circulating microRNAs (ci-miRNAs) profile in Behçet's syndrome (BS).Total RNA was extracted from platelets-free plasma (PFP) samples obtained from 16 BS patients and 18 healthy controls. Ci-miRNAs profiling was conducted by using dedicated Agilent microarray hybridization and data extraction technology. Statistical analysis of data extracted from microarray scanning revealed the deregulation of 36 ci-miRNAs, which turned out be differentially expressed between BS patients and healthy controls. Detailed experimental methods and data analysis were described here.The raw and normalized microarray data were deposited into Gene Expression Omnibus (GEO) under accession number GSE145191.

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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